[Download] "Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models" by Joel S. Owen & Jill Fiedler-Kelly * eBook PDF Kindle ePub Free

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eBook details

• Title: Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models
• Author : Joel S. Owen & Jill Fiedler-Kelly
• Release Date : January 19, 2014
• Genre: Pharmacology & Toxicology,Books,Professional & Technical,Medical,
• Pages : * pages
• Size : 16051 KB

Description

This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis.
• Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects
• Provides examples of nonlinear modeling concepts and estimation basics with discussion on  the model building process and applications of empirical Bayesian estimates in the drug development environment
• Includes detailed chapters on data set structure, developing control streams for modeling and simulation, model applications, interpretation of NONMEM output and results, and quality control
• Has datasets, programming code, and practice exercises with solutions, available on a supplementary website

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